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Other nicely studied nAChR genes involve the CHRNA4 and CHRNB2, that have been connected as Autosomal Dominant Nocturnal Frontal Lobe Epilepsy (ADNFLE) genes.[forty two][46] Equally of those nAChR subunits are existing from the brain and also the occurrence of mutations in both of these subunits trigger a generalized variety of epilepsy. Examples i